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18TH ANNUAL • MULTIPLE SCLEROSIS & NEUROIMMUNOLOGY

Mellen Center Update
in Multiple Sclerosis

2026 Video Course

A forward-looking clinical update on multiple sclerosis,
neuroimmunology, disease-modifying therapies, progressive disease,
NMOSD, rehabilitation and emerging technologies.

16 VIDEO LECTURES
VIDEO-ONLY COURSE




DIGITAL CONTENT INCLUDED: VIDEO LECTURES ONLY

PDF lecture files are not included with this course.



THE 2026 MS CLINICAL UPDATE

Multiple Sclerosis Care
Is Entering a New Era.

The 2026 Mellen Center Update in Multiple
Sclerosis
brings together clinically focused education addressing
major developments in multiple sclerosis and related neuroimmunologic disorders.

The program translates recent advances in MS research into practical
clinical approaches, with attention to treatment selection, disease progression,
rehabilitation, infection risk and complex neuroimmunologic disease.



2026 FEATURE TOPIC

BTK Inhibitors &
Progressive Multiple Sclerosis

One of the major highlights of the program examines emerging
Phase 3 evidence surrounding Bruton’s tyrosine kinase inhibitors
and their potential implications for progressive multiple sclerosis.

FEATURED LECTURE


BTK Inhibitors in Multiple Sclerosis

Integrating Phase 3 Trial Evidence to Address Progressive Disease

Jiwon Oh • 47:22



MS CLINICAL INTELLIGENCE MAP

What Is Changing in MS Care?

01 • THERAPY

Disease-Modifying Therapies

Treatment selection, monitoring and infection-risk considerations.

02 • PROGRESSION

Progressive Multiple Sclerosis

Early recognition, monitoring and emerging therapeutic strategies.

03 • NEUROIMMUNOLOGY

NMOSD & Autoimmune Encephalitis

Treatment selection, antibody testing and therapeutic sequencing.

04 • FUNCTION

Rehabilitation & Disability

Fatigue, cognition, mobility, spasticity and long-term rehabilitation.

05 • FUTURE

Artificial Intelligence

The expanding role of AI in diagnosis, clinical decisions and patient outcomes.



DISEASE-MODIFYING THERAPY

Control Disease.
Manage Treatment Risk.

Modern MS treatment requires clinicians to balance disease control with
the risks associated with long-term immunomodulatory therapy.

DMT Selection & Monitoring
Infection Risk Profiles
Practical Infection Prevention
Real-World Case Management
Vaccination Considerations



BEYOND CONVENTIONAL MS

Complex Neuroimmunologic Disorders

NMOSD


AQP4+ Neuromyelitis Optica Spectrum Disorder

Practical considerations surrounding first-line therapy and
new FDA-approved monoclonal antibodies.

AUTOIMMUNE NEUROLOGY


Autoimmune Encephalitis

A practical approach to diagnosis, antibody testing
and treatment sequencing.



MS REHABILITATION

Treatment Is More Than
Disease Modification.

The program places substantial emphasis on long-term function,
mobility, fatigue and interdisciplinary rehabilitation.

Tele-Exercise
Cognitive Training
Cognitive Fatigue & Evidence-Based Pacing
Goal-Oriented Rehabilitation
Wheelchair Evaluation & Planning
Fatigue • Heat Intolerance • Spasticity



PERSONALIZED MS CARE

Different Patients.
Different Clinical Challenges.

Hormonal Influences
Clinical insights from puberty through menopause.
Older Adults with MS
DMT transition, psychosocial care and rehabilitation.
Men with MS
Engagement, coping and quality-of-life support.
Social Determinants & Equity
Strategies to reduce loss to follow-up and improve continuity of care.



EMERGING TECHNOLOGY

Artificial Intelligence
in Multiple Sclerosis

The course examines the expanding role of artificial intelligence
and its potential impact on diagnosis, treatment, clinical decision-making
and patient outcomes.


Integrating AI-Driven Insights in Multiple Sclerosis

Moein Amin • 20:54



LEARNING OBJECTIVES

After Completing the Course

Review updates in MS disease-modifying therapies and BTK inhibitors.
Understand and manage infection risks associated with DMTs.
Review recent treatment developments in NMOSD.
Apply practical approaches to autoimmune encephalitis.
Understand contemporary MS rehabilitation strategies.
Recognize mechanisms contributing to MS disability progression.
Understand hormonal influences on multiple sclerosis.
Apply interdisciplinary approaches to fatigue, heat intolerance and spasticity.
Understand emerging applications of artificial intelligence in MS care.
Improve rehabilitation and mobility planning.



COMPLETE PROGRAM

16 Video Lectures

Complete 2026 Mellen Center Multiple Sclerosis & Neuroimmunology video curriculum.

01
Choosing First-Line Therapy in AQP4+ NMOSD
Kaitlyn Palmer • Justin R. Abbatemarco • 25:49
02
Men with MS: Engagement, Coping & Quality-of-Life Support
Amy Sullivan • 07:11
03
Older-Adult MS: Psychosocial Care, DMT Transition & Rehabilitation
Grace Tworek • 08:19
04
Multiple Sclerosis and Social Determinants
Brianne Markley • 06:29
05
Multiple Sclerosis Vaccination Strategies
Brent Sokola • 19:46
06
Integrating AI-Driven Insights in Multiple Sclerosis
Moein Amin • 20:54
07
MS DMTs: Infection Risk Profiles & Prevention Strategies
Robert Fox • 26:47
08
MS Case Studies: Managing Infection Risk with DMTs
Hilary Young • Jennifer Basalla • Shauna Gales • Jennifer Sedlak • 29:11
09
MS Progression: Early Recognition & Monitoring
Devon Conway • Amjad Samara • 28:39
10
MS Hormone Modulation: Puberty to Menopause
Alise Carlson • Katherine Havard-Coiro • 23:18
11
BTK Inhibitors in Multiple Sclerosis
Jiwon Oh • 47:22
12
MS Rehabilitation Strategies
Francois Bethoux • 34:37
13
Autoimmune Encephalitis: Diagnosis, Antibody Testing & Treatment Sequencing
Amy Kunchok • 34:09
14
MS Cognitive Fatigue: Evidence-Based Pacing
Danielle Brown • 30:12
15
MS Wheelchair Evaluation: Proactive Five-Year Coverage Planning
Alyssa Decarlo • 33:59
16
MS Symptom Triad: Fatigue, Heat Intolerance & Spasticity
Danielle Brown • Alyssa Decarlo • Kellie Keim • Kaitlin Sparks • 34:34



TARGET AUDIENCE

Who Is This Course For?

Neurologists & Multiple Sclerosis Specialists
Neuroimmunologists & Physicians
Nurses & Advanced Practice Providers
Physical & Occupational Therapists
Speech Therapists & Rehabilitation Specialists
Psychologists & Other MS Care Professionals



WHY THIS PROGRAM?

From Disease Modification
to Whole-Patient MS Care

✓ Emerging MS Therapies
✓ Phase 3 BTK Inhibitor Evidence
✓ Progressive MS Monitoring
✓ DMT Safety & Infection Prevention
✓ NMOSD & Autoimmune Encephalitis
✓ Interdisciplinary Rehabilitation
✓ AI & Emerging Clinical Technology



MULTIPLE SCLEROSIS • NEUROIMMUNOLOGY • 2026

Recognize Progression.
Navigate New Therapies.
Advance MS Care.

A focused 2026 clinical update covering disease-modifying therapies,
BTK inhibitors, progressive MS, NMOSD, autoimmune encephalitis,
rehabilitation, symptom management and artificial intelligence.

16 VIDEO LECTURES • VIDEO-ONLY COURSE
18TH ANNUAL MULTIPLE SCLEROSIS & NEUROIMMUNOLOGY PROGRAM

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