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5TH ANNUAL CLINICAL CONFERENCE • 2026

Psychedelic-Assisted
Psychotherapy

Clinical Complexities, Evidence & Therapeutic Practice

An advanced clinical conference exploring the therapeutic,
psychological, spiritual and safety dimensions of
psychedelic-assisted psychotherapy.


FEB 26–27, 2026


VIDEOS


PDFs



Developed by Harvard Medical School Teaching Hospitals
  •  
Offered by Cambridge Health Alliance



COURSE OVERVIEW

Beyond the Psychedelic Session

Psychedelic-assisted psychotherapy involves more than the pharmacologic
effects of a psychedelic medicine. Clinical care may also involve
complex emotional experiences, therapeutic relationships, preparation,
non-ordinary states of consciousness and post-session integration.

This 5th annual clinical conference
examines the rapidly evolving field through clinical cases,
vignettes, expert discussions and panel sessions.

The program addresses scientific evidence alongside therapeutic frameworks,
spiritual and existential experiences, somatic phenomena,
potential adverse effects and multidisciplinary approaches to care.



THE THERAPEUTIC EXPERIENCE FRAMEWORK

Five Dimensions of Psychedelic-Assisted Psychotherapy

01 • PREPARATION

Set, Setting & Therapeutic Structure

Explore the therapeutic environment, clinical preparation
and considerations surrounding set and setting.

02 • EXPERIENCE

Non-Ordinary States

Examine emotional, somatic, transpersonal and altered experiences
that may emerge during psychedelic therapy.

03 • MEANING

Spiritual & Existential Dimensions

Consider grief, awe, spirituality, metaphysical questions
and different frameworks for understanding psychedelic experiences.

04 • THERAPY

Clinical Response & Integration

Understand therapeutic frameworks, non-directive approaches,
behavioral interventions and complex clinical encounters.

05 • SAFETY

Risk Recognition & Harm Reduction

Recognize challenging experiences, potential adverse effects
and strategies designed to minimize harm.



THE CENTRAL CLINICAL QUESTION

What Happens When the
Experience Becomes Complex?

Psychedelic psychotherapy may involve experiences that do not fit neatly
into conventional therapeutic categories. The conference examines how
clinicians can approach these situations with greater clinical awareness.

Grief & Powerful Emotional States
Awe & Transpersonal Experiences
Spiritual & Existential Experiences
Ego Dissolution
Somatic Experiences
Difficult or Adverse Psychedelic Experiences



PAP CLINICAL PATHWAY

From Preparation to Integration

STEP 01

PREPARE

↓
STEP 02

ESTABLISH SET & SETTING

↓
STEP 03

NAVIGATE THE EXPERIENCE

↓
STEP 04

RECOGNIZE COMPLEXITY & RISK

↓
STEP 05

PROCESS & INTEGRATE



LEARNING OBJECTIVES

What You Will Learn

PAP Foundations

Understand the core principles and structure of psychedelic-assisted psychotherapy.

Medicines & Clinical Applications

Identify commonly used medicines in PAP and review their clinical applications.

Scientific Evidence

Review current clinical evidence supporting psychedelic-assisted psychotherapy.

Emotional & Transpersonal States

Recognize grief, awe and transpersonal experiences that may emerge during therapy.

Spiritual & Existential Dimensions

Explore spiritual, existential and metaphysical aspects of psychedelic therapy.

Cross-Cultural Perspectives

Compare Western and Indigenous perspectives on non-ordinary states of consciousness.

Safety & Harm Reduction

Identify potential risks and adverse effects and consider strategies to minimize harm.

Somatic Experiences

Recognize common somatic experiences that may occur during psychedelic sessions.

Non-Directive Therapy

Explore the non-directive therapeutic approach used in psilocybin sessions.

Multidisciplinary Care

Understand collaboration across disciplines when navigating complex PAP cases.



DAY 01 • THURSDAY

February 26, 2026

Foundations • Clinical Outcomes • Set & Setting • Somatic & Spiritual Experience
Back to Basics
The Method and the Medicines of PAP
Clinical Outcomes of Psychedelic Therapy
Neglected Considerations for Set & Settings
Somatic Experiences in Psychedelic Therapy
Religious & Spiritual Perspectives in PAP
Panel Discussions & Case-Based Learning



DAY 02 • FRIDAY

February 27, 2026

Culture • Ego Dissolution • Adverse Experiences • OCD • Collaboration
Western vs Indigenous Approaches
Perspectives on psychedelic and non-ordinary experiences.
Ego Dissolution Case Studies
Managing Difficult or Adverse Psychedelic Experiences
Psychedelic-Boosted Behavioral Therapy for OCD
Interdisciplinary Collaboration in PAP
Clinical Complexities in Psychedelic Therapy



MULTIPLE PERSPECTIVES

One Experience.
Different Ways of Understanding It.

CLINICAL

Therapeutic Framework

Clinical evidence, therapeutic technique and treatment structure.

EXPERIENTIAL

Patient Experience

Emotional, somatic and non-ordinary states occurring during therapy.

SPIRITUAL

Meaning & Transcendence

Spiritual, religious, existential and metaphysical interpretations.

CULTURAL

Western & Indigenous Perspectives

Different frameworks for understanding non-ordinary states of consciousness.



PATIENT SAFETY

When the Experience
Does Not Go as Expected

The program examines potential risks and challenging experiences
that may arise during psychedelic-assisted psychotherapy,
with attention to harm reduction and clinical response.

✓ Recognizing Potential Adverse Effects
✓ Navigating Difficult Experiences
✓ Understanding Clinical Complexity
✓ Strategies to Minimize Harm
✓ Improving Patient Safety



TARGET AUDIENCE

Who Should Attend?

Designed for healthcare professionals involved in mental health,
psychotherapy and related clinical fields.

Psychiatrists
Primary Care Physicians
Psychologists
Social Workers & Counselors
Nurses
Mental Health Clinicians
Researchers & Other Healthcare Professionals



DIGITAL COURSE CONTENT

Included With This Course

▶


Conference Videos

Recorded educational sessions from the 2026 clinical conference.

▤


Course PDFs

Supporting PDF educational materials included with the course.



COURSE SNAPSHOT

2026 Clinical Conference

EVENT
5th Annual Clinical Conference
DATES
February 26–27, 2026
FORMAT
Live Online or In Person
CONTENT
Videos + PDFs
DEVELOPED BY
Harvard Medical School Teaching Hospitals
OFFERED BY
Cambridge Health Alliance



PSYCHEDELIC-ASSISTED PSYCHOTHERAPY • 2026

Understand the Experience.
Navigate the Complexity.
Strengthen Clinical Care.

An advanced clinical program exploring psychedelic-assisted psychotherapy
through evidence, therapeutic frameworks, complex experiences,
patient safety and multidisciplinary clinical perspectives.

VIDEOS   •   PDFs   •   2-DAY CONFERENCE
FEBRUARY 26–27, 2026

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